4-Hydroxycinnamic Acid: Potent Phenolic Compound for Advanced Biomedical Research
1. Molecular Identity
- Chemical Name: 3-(4-Hydroxyphenyl)-2-propenoic acid
- CAS Number: 501-98-4
- Source: Naturally occurring in various plants; also synthetically produced
2. Biochemical Significance
4-Hydroxycinnamic acid, also known as p-coumaric acid, is a hydroxycinnamic acid with diverse biological activities. Its unique molecular structure contributes to its potent antioxidant, anti-inflammatory, and potential therapeutic properties, making it a compound of significant interest in nutritional and pharmaceutical research.
3. Key Properties of 4-Hydroxycinnamic Acid
- Antioxidant: Exhibits strong free radical scavenging activity
- Anti-inflammatory: Demonstrates ability to modulate inflammatory responses
- Antimicrobial: Shows potential against various pathogens
- Chemopreventive: Indicates promise in cancer prevention studies
4. Potential Research Applications
- Oxidative stress and aging studies
- Cancer research and chemoprevention
- Cardiovascular health investigations
- Skin health and photoprotection research
5. Current Research Focus
Ongoing studies are investigating 4-Hydroxycinnamic acid’s effects on:
- Cellular antioxidant defense mechanisms
- Inflammatory signaling pathways
- Microbial growth inhibition
- UV-induced skin damage prevention
6. Formulation Challenges and Innovations
Researchers are actively working on:
- Enhancing stability and bioavailability
- Developing targeted delivery systems for improved efficacy
- Creating synergistic combinations with other bioactive compounds
7. Regulatory Considerations
4-Hydroxycinnamic acid (CAS 501-98-4) is Generally Recognized as Safe (GRAS) for use as a flavoring substance. Its use in specific therapeutic applications would require comprehensive safety and efficacy evaluations to meet regulatory standards.
8. Future Research Directions
The scientific community anticipates:
- Advanced clinical trials for antioxidant and anti-inflammatory applications
- Exploration of 4-Hydroxycinnamic acid’s potential in nutraceutical formulations
- Investigation of its role in epigenetic modulation
9. Collaborative Opportunities
We invite nutritionists, pharmacologists, dermatologists, and academic institutions to explore the research potential of 4-Hydroxycinnamic acid. For inquiries, collaborations, or to discuss how this compound can benefit your research projects, please contact us at sales@nstchemicals.com.
Join us in advancing biomedical research with 4-Hydroxycinnamic acid – a versatile phenolic compound at the forefront of antioxidant and anti-inflammatory studies.
