Bakuchiol: Innovative Meroterpene for Advanced Dermatological Research
1. Molecular Identity
- Chemical Name: 4-[(1E,3S)-3-ethenyl-3,7-dimethylocta-1,6-dienyl]phenol
- CAS Number: 10309-37-2
- Source: Naturally occurring in Psoralea corylifolia seeds and other plant sources
2. Biochemical Significance
Bakuchiol is a unique meroterpene with retinol-like properties. Its distinctive molecular structure contributes to its potent antioxidant, anti-aging, and skin-renewing effects, making it a compound of significant interest in dermatological research and cosmeceutical applications.
3. Key Properties of Bakuchiol
- Retinol-like Activity: Demonstrates skin-renewing effects similar to retinol
- Antioxidant: Exhibits strong free radical scavenging capabilities
- Anti-inflammatory: Shows potential in reducing skin inflammation
- Antimicrobial: Displays activity against certain skin pathogens
4. Potential Research Applications
- Anti-aging skincare formulations
- Acne treatment studies
- Skin pigmentation research
- Wound healing investigations
5. Current Research Focus
Ongoing studies are investigating Bakuchiol’s effects on:
- Collagen production and skin elasticity
- Melanin synthesis and hyperpigmentation
- Sebum regulation in acne-prone skin
- Skin barrier function and hydration
6. Formulation Challenges and Innovations
Researchers are actively working on:
- Enhancing stability in various cosmetic formulations
- Developing targeted delivery systems for improved skin penetration
- Creating synergistic combinations with other active ingredients
7. Regulatory Considerations
Bakuchiol (CAS 10309-37-2) is generally recognized as safe for cosmetic use. Its development for specific therapeutic applications would require comprehensive safety and efficacy evaluations to meet regulatory standards.
8. Future Research Directions
The scientific community anticipates:
- Advanced clinical trials comparing Bakuchiol to established skincare actives
- Exploration of its potential in treating various skin disorders
- Investigation of its mechanisms of action at the molecular level
9. Collaborative Opportunities
We invite dermatologists, cosmetic scientists, pharmacologists, and academic institutions to explore the research potential of Bakuchiol. For inquiries, collaborations, or to discuss how this compound can benefit your research projects, please contact us at sales@nstchemicals.com.
Join us in advancing dermatological research with Bakuchiol – a promising meroterpene at the forefront of natural anti-aging and skin health studies.
