Baohuoside I: Novel Flavonoid for Advanced Pharmaceutical Research

1. Molecular Identity

• Chemical Name: 7-O-β-D-glucopyranosyl-3′,5-dihydroxy-4′-methoxyflavone
• CAS Number: 113558-15-9
• Source: Extracted from Epimedium species, particularly Epimedium koreanum

2. Biochemical Significance

Baohuoside I is a flavonoid glycoside with a unique molecular structure that contributes to its diverse biological activities. Its presence in traditional medicinal plants, particularly in the genus Epimedium, makes it a compound of significant interest in natural product research and drug discovery.

3. Key Properties

• Estrogenic Activity: Demonstrates potential phytoestrogen effects
• Anti-osteoporotic: Shows promise in promoting bone health
• Neuroprotective: Exhibits potential in protecting neuronal cells
• Anticancer Potential: Indicates promising effects in various cancer models

4. Potential Research Applications

• Osteoporosis and bone metabolism studies
• Neurodegenerative disease investigations
• Cancer research and drug development
• Hormonal and reproductive health studies

5. Current Research Focus

Ongoing studies are investigating Baohuoside I’s effects on:

• Bone density and osteoblast/osteoclast activity
• Neuroprotection mechanisms in various brain disorders
• Various cancer types and mechanisms of action
• Estrogen receptor modulation and related pathways

6. Formulation Challenges and Innovations

Researchers are actively working on:

• Enhancing bioavailability and solubility
• Developing targeted delivery systems for improved efficacy
• Creating stable formulations for various research applications

7. Regulatory Considerations

As a naturally occurring compound, Baohuoside I’s (CAS 113558-15-9) regulatory status is evolving. Its use in specific therapeutic applications would require comprehensive safety and efficacy evaluations to meet regulatory standards.

8. Future Research Directions

The scientific community anticipates:

• Advanced preclinical studies for bone health and neurological indications
• Exploration of Baohuoside I’s potential in hormone-dependent cancers
• Investigation of structure-activity relationships for optimized derivatives

9. Collaborative Opportunities

We invite pharmacologists, oncologists, neuroscientists, and academic institutions to explore the research potential of Baohuoside I. For inquiries, collaborations, or to discuss how Baohuoside I can benefit your research projects, please contact us at [email protected].

Join us in advancing pharmaceutical research with Baohuoside I – a promising flavonoid at the intersection of traditional medicine and modern drug discovery.