Cholesteryl Acetate: Essential Cholesterol Derivative for Advanced Lipid Research
1. Molecular Identity
- Chemical Name: (3β)-Cholest-5-en-3-yl acetate
- CAS Number: 604-35-3
- Source: Synthetically produced from cholesterol
2. Biochemical Significance
Cholesteryl acetate is a crucial cholesterol ester with significant importance in lipid metabolism research. Its unique molecular structure, featuring an acetyl group attached to cholesterol, makes it a valuable tool in studying lipid dynamics, membrane structure, and related physiological processes.
3. Key Properties of Cholesteryl Acetate
- Lipid Metabolism Marker: Serves as an important intermediate in cholesterol metabolism
- Membrane Modulator: Influences membrane fluidity and organization
- Stability: Offers enhanced stability compared to free cholesterol
- Model Compound: Useful in lipid bilayer and liposome studies
4. Potential Research Applications
- Lipid metabolism and transport studies
- Membrane structure and function investigations
- Atherosclerosis and cardiovascular disease research
- Liposome and drug delivery system development
5. Current Research Focus
Ongoing studies are investigating Cholesteryl acetate’s role in:
- Cholesterol homeostasis and intracellular trafficking
- Lipid raft formation and cellular signaling
- Development of cholesterol-lowering therapies
- Nanoparticle-based drug delivery systems
6. Formulation Challenges and Innovations
Researchers are actively working on:
- Enhancing solubility in various experimental media
- Developing stable formulations for in vitro and in vivo studies
- Creating novel cholesterol-based nanocarriers
7. Regulatory Considerations
Cholesteryl acetate (CAS 604-35-3) is primarily used in research settings. Its use in specific applications may be subject to regulatory oversight depending on the intended use and jurisdiction.
8. Future Research Directions
The scientific community anticipates:
- Advanced studies on the role of cholesteryl esters in disease pathogenesis
- Exploration of its potential in personalized lipid-lowering therapies
- Investigation of its interactions with other lipids and proteins
9. Collaborative Opportunities
We invite lipid biochemists, cell biologists, pharmaceutical researchers, and academic institutions to explore the research potential of Cholesteryl acetate. For inquiries, collaborations, or to discuss how this compound can benefit your research projects, please contact us at sales@nstchemicals.com.
Join us in advancing lipid research with Cholesteryl acetate – a key cholesterol derivative at the forefront of membrane biology and cardiovascular studies.
