Glycyrrhetinic Acid : Potent Triterpenoid for Advanced Biomedical Research

1. Molecular Identity

• Chemical Name: 3β-Hydroxy-11-oxo-18β,20β-olean-12-en-29-oic acid
• CAS Number: 471-53-4
• Source: Naturally occurring in licorice root (Glycyrrhiza glabra)

2. Biochemical Significance

Glycyrrhetinic Acid is a pentacyclic triterpenoid with diverse biological activities. Its unique molecular structure contributes to its potent anti-inflammatory, hepatoprotective, and potential anticancer properties, making it a compound of significant interest in pharmaceutical research and natural product studies.

3. Key Properties of Glycyrrhetinic Acid

• Anti-inflammatory: Exhibits strong ability to modulate inflammatory responses
• Hepatoprotective: Demonstrates potential in protecting liver cells
• Antiviral: Shows promise against certain viral infections
• Skin-beneficial: Indicates efficacy in various dermatological applications

4. Potential Research Applications

• Inflammatory disorder studies
• Liver disease investigations
• Dermatological research
• Cancer and cell proliferation studies

5. Current Research Focus

Ongoing studies are investigating Glycyrrhetinic Acid’s effects on:

• Inflammatory signaling pathways in various tissues
• Hepatic enzyme activities and liver function
• Skin barrier function and wound healing
• Cancer cell growth inhibition mechanisms

6. Formulation Challenges and Innovations

Researchers are actively working on:

• Enhancing bioavailability through novel delivery systems
• Developing targeted formulations for specific applications
• Creating synergistic combinations with other bioactive compounds

7. Regulatory Considerations

Glycyrrhetinic Acid (CAS 471-53-4) is used in various cosmetic products and research settings. Its development for specific therapeutic applications would require comprehensive safety and efficacy evaluations to meet regulatory standards.

8. Future Research Directions

The scientific community anticipates:

• Advanced clinical trials for inflammatory and liver disorders
• Exploration of Glycyrrhetinic Acid’s potential in cancer therapies
• Investigation of its mechanisms of action at the molecular level

9. Collaborative Opportunities

We invite hepatologists, dermatologists, oncologists, and academic institutions to explore the research potential of Glycyrrhetinic Acid. For inquiries, collaborations, or to discuss how this compound can benefit your research projects, please contact us at sales@nstchemicals.com.

Join us in advancing biomedical research with Glycyrrhetinic Acid – a powerful triterpenoid at the forefront of natural product-based therapeutic strategies.