Gossypol Acetate: Potent Polyphenolic Compound for Advanced Biomedical Research

1. Molecular Identity

• Chemical Name: 2,2′-Bis(8-formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene) diacetate
• CAS Number: 12542-36-8
• Source: Derived from gossypol, a natural compound found in cotton seeds and other plants of the Malvaceae family

2. Biochemical Significance

Gossypol acetate is a semi-synthetic derivative of gossypol, featuring enhanced stability and solubility. Its unique molecular structure contributes to diverse biological activities, making it a compound of significant interest in various fields of biomedical research.

3. Key Properties

• Antifertility Agent: Demonstrates potential in male contraception studies
• Anticancer Activity: Shows promise in inhibiting various cancer cell lines
• Antioxidant Capacity: Exhibits free radical scavenging abilities
• Antimicrobial Properties: Displays activity against certain pathogens

4. Potential Research Applications

• Reproductive biology and contraception studies
• Cancer research and drug development
• Antioxidant and free radical investigations
• Antimicrobial compound screening

5. Current Research Focus

Ongoing studies are investigating Gossypol acetate’s effects on:

• Mechanisms of action in various cancer types
• Male reproductive system and spermatogenesis
• Mitochondrial function and energy metabolism
• Potential synergistic effects with established therapies

6. Formulation Challenges and Innovations

Researchers are actively working on:

• Enhancing targeted delivery to specific tissues
• Developing controlled-release formulations
• Improving solubility and bioavailability

7. Safety and Handling Considerations

Due to its potent biological effects, Gossypol acetate (CAS 12542-36-8) should be handled with caution in research settings. Proper safety protocols must be followed, and its use is strictly limited to controlled laboratory environments.

8. Future Research Directions

The scientific community anticipates:

• Advanced preclinical studies in cancer and reproductive health
• Further exploration of structure-activity relationships
• Development of less toxic analogues with retained efficacy

9. Collaborative Opportunities

We invite cancer researchers, reproductive biologists, pharmacologists, and academic institutions to explore the research potential of Gossypol acetate. For inquiries, collaborations, or to discuss how Gossypol acetate can benefit your research projects, please contact us at sales@nstchemicals.com.

Join us in advancing biomedical research with Gossypol acetate – a powerful compound at the intersection of natural product chemistry and innovative therapeutic strategies.