Icaritin: Unveiling the Potential of a Potent Flavonoid

1. Molecular Identity

• Chemical Name: 3,5,7-Trihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)-4H-chromen-4-one
• CAS Number: 118525-40-9
• Source: Derived from Epimedium species, commonly known as Horny Goat Weed

2. Biochemical Significance

Icaritin is a prenylated flavonoid that exhibits diverse pharmacological activities. Its unique molecular structure allows it to interact with various cellular targets, contributing to its broad spectrum of biological effects.

3. Key Therapeutic Properties

• Osteogenic: Promotes bone formation and prevents bone loss
• Anticancer: Demonstrates potential in inhibiting tumor growth and metastasis
• Neuroprotective: Shows promise in protecting neuronal cells
• Immunomodulatory: Regulates immune system function

4. Potential Applications

• Osteoporosis treatment and prevention
• Cancer therapy research
• Neurodegenerative disease interventions
• Immune system modulation studies

5. Current Research Focus

Ongoing studies are investigating Icaritin’s effects on:

• Bone metabolism and osteoporosis
• Various cancer types and mechanisms
• Alzheimer’s and Parkinson’s diseases
• Autoimmune disorders

6. Formulation Challenges and Innovations

Researchers are actively working on:

• Enhancing bioavailability through novel delivery systems
• Developing targeted formulations for specific tissues
• Creating stable, long-lasting preparations

7. Regulatory Considerations

As a naturally derived compound, Icaritin’s (CAS 118525-40-9) regulatory status is evolving. Ongoing research aims to establish its safety profile and efficacy for potential therapeutic applications.

8. Future Directions

The scientific community anticipates:

• Advanced clinical trials for specific indications
• Development of semi-synthetic derivatives with enhanced properties
• Exploration of synergistic effects with other bioactive compounds

9. Collaborative Opportunities

We invite researchers, pharmaceutical companies, and healthcare professionals to explore the therapeutic potential of Icaritin. For inquiries, collaborations, or to discuss how Icaritin can benefit your research or product development, please contact us at sales@nstchemicals.com.

Join us in unlocking the potential of Icaritin – a promising flavonoid at the forefront of natural product research and innovative therapeutic strategies.